Select Agent Program

Intiated in 1996 with the Antiterrorism and Effective Death Penalty Act, and bolstered by the USA Patriot Act of 2001, and the Public Health Security and Bioterrorism Preparedness and Response Act of 2002, the National Select Agent Registry (NSAR) Program oversees the possession, use and transfer of biological select agents and toxins that have the potential to pose a severe threat to public or environmental health. Possession of the specified agents or toxins without registration carries severe civil and criminal penalties.

Click here for the list of Select Agents and Toxins.

The following toxins are not subject to federal oversight if the amount under the control of a principal investigator, treating physician or veterinarian, does not exceed, at any time, the amounts indicated in the table below.

HHS Toxins [§73.3(d)(3)] Amount
Abrin100 mg
Botulinum neurotoxins0.5 mg
Short, paralytic alpha conotoxins100 mg
Diacetoxyscirpenol (DAS)1000 mg
Ricin100 mg
Saxitoxin100 mg
Staphylococcal Enterotoxins (Subtypes A, B, C, D, and E)5 mg
T-2 toxin1000 mg
Tetrodotoxin100 mg